Desarrollo de nuevas estrategias de inmunoterapia

INFORMACIÓN DE CONTACTO
Foto Equipo
Grupo de Investigación

LASARTE SAGASTIBELZA, JUAN JOSE
  Correo Electrónico jjlasarte@unav.es


Foto Grupo

ARDAIZ IRIARTE, NURIA
BELSUE URQUIZU, VIRGINA
Repáraz, D, Casares, N, Fuentes, A, Navarro, F "Establishment of a murine hepatocellular carcinoma model by hydrodynamic injection and characterization of the immune tumor microenvironment".
 Methods Cell Biol.. 185: 79 - 97. 2024. [doi:10.1016/bs.mcb.2024.02.006]
Arrizabalaga, L, Di Trani, CA, Risson, A, Belsúe, V, Gomar, C, Ardaiz, N, Berrondo, P, Aranda, F, Bella, A "Peritoneal carcinomatosis in mouse models".
 Methods Cell Biol.. 185: 67 - 78. 2024. [doi:10.1016/bs.mcb.2024.02.005]
Aparicio, B, Silva, L, Ruiz, M, Llópiz, D, Repáraz, D, Theunissen, P, Tamayo, I, Egea, J, Igea, A, Smerdou, C, Peñas, M, Perpiñá, C, Matilla, A, Varela, M, Reig, M, de la Torre-alaez, M, Argemí, J, Sangro, B, Hervás-Stubbs, S, Sarobe, P "Immunogenicity of neoantigens from hepatocellular carcinoma patients treated with a combined radioimmunotherapy".
 OncoImmunology. 15(1): 2645280. 2026. [doi:10.1080/2162402X.2026.2645280]
imagen
Gomis, G, Arrieta-Aranzueque, S, Herrero, C, Azpilikueta, A, Molero-Glez, P, Cuesta, R, Streitlein, L, Kleist, C, Mier, W, Garrido, MJ, Rochira, F, Pineda-Lucena, A, Berraondo, P, Melero, I "Monomethyl-auristatin E-based anti-CD137 (4-1BB) antibody drug conjugates are not suitable tools to deplete activated T lymphocytes".
 Immunobiology. 231(4): 153205. 2026. [doi:10.1016/j.imbio.2026.153205]
imagen
Argemi, J, Hervas-Stubbs, S, Conde, E, Martinez-Montes, A, Li, ZY, Tamayo, I, Cross, A, Piulats, JM, Matilla, A, Iñarrairaegui, M, Varela, M, de la Torre, M, Reig, M, Issa, F, Sharma, A, Ginhoux, F, Fabregat, I, de Andrea, CE, Sarobe, P, Sangro, B "Stromal remodeling and neoantigen clonality as used to evaluate benefit from SIRT-nivolumab in HCC.".
 J. Clin. Oncol.. 44(16_SUPPL): 16285 - 16285. 2026. [doi:10.1200/JCO.2026.44.16_suppl.e16285]
Korilis, AG, Lecumberri, A, Alexandru, R, Domínguez, PP, Ardaiz, N, Belsue, V, de Andrea, CE, Alsina, M, Berraondo, P "Characterization of therapeutic targets for cancer immunotherapy in gastroesophageal cancer samples".
 Eur. J. Clin. Invest.. 56. 2026. 
Ziogas, DC, Theocharopoulos, C, Berraondo, P, Piulats, JM, Gogas, H "Editorial: Current insights in melanoma immunology, immune escape and immunotherapy advances".
 Front. Immunol.. 17: 1868805. 2026. [doi:10.3389/fimmu.2026.1868805]
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Alejos, CC, Llopiz, D, Ardila, AM, Ruiz, M, Silva, L, Mancheño, U, Miraval, E, Echeveste, J, Hervás-Stubbs, S, Sogbe, M, Argemi, J, Sangro, B, Sarobe, P "Development of ex vivo models to study the response to immunotherapy in hepatocellular carcinoma".
 J. Hepatol.. 84: 364 - 365. 2026. 
Adan-Villaescusa, E, Castello-Uribe, B, Uriarte, I, Santamaria, E, Barbero, R, Belzunce, M, Lopez-Pascual, A, Latasa, MU, Elurbide, J, Valbuena-Goiricelaya, E, Mesropian, A, Cano-Segarra, G, de Sande, AH, Nevi, L, Carotti, S, Vespasiani-Gentilucci, U, Prosper, F, Pineda-Lucena, A, Sangro, B, Argemi, J, Berraondo, P, Sarobe, P, Gris-Oliver, A, Pinyol, R, Llovet, JM, Arechederra, M, Berasain, C, Cocozaki, A, Gibaja, V, Avila, MA, Fernandez-Barrena, MG "Histone methyl-transferase G9a inhibition boosts the efficacy of immune checkpoint inhibitors in experimental hepatocellular carcinoma".
 Cell Rep. Med.. 7(4): 102717. 2026. [doi:10.1016/j.xcrm.2026.102717]
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Armero, M, Smolkin, M, Garcia-Dominguez, M, Berraondo, P, Melero, I, Galvez-Cancino, F "Facts and Hopes in Harnessing Macrophage-Mediated Antibody-Dependent Cellular Phagocytosis for Cancer Immunotherapy".
 Clin. Cancer Res.. 32(3): 455 - 464. 2026. [doi:10.1158/1078-0432.CCR-25-0434]
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Eficacia y toxicidad de células CAR-T modificadas para la expresión de una quimera IL-15/IL-15Ra; y estudio metabolómico del microambiente tumoral Autores: Inés Sánchez Moreno | Participantes: LOZANO, TERESA, LASARTE, JUAN JOSE Tesis Doctoral. F.Inicio: . F.Lectura: 07/11/2025. ESP. UNIVERSIDAD DE NAVARRA. .
Locoregional Immunotherapy Strategies for Peritoneal Carcinomatosis Autores: ARRIZABALAGA, LEIRE | Participantes: Berraondo, Pedro, ARANDA, FERNANDO Tesis Doctoral. F.Inicio: . F.Lectura: 25/06/2025. ESP. UNIVERSIDAD DE NAVARRA. .
Immunomodulatory activity of natural compounds againstcancer Autores: Miriam Ezcurra Hualde | Participantes: Berraondo, Pedro, ARANDA, FERNANDO Tesis Doctoral. F.Inicio: . F.Lectura: 09/04/2025. ESP. UNIVERSIDAD DE NAVARRA. .
Evaluation of Modified Vaccinia virus Ankara based locoregional immunotherapy in peritoneal carcinomatosis models Autores: BELLA, ANGELA | Participantes: Berraondo, Pedro, ARANDA, FERNANDO Tesis Doctoral. F.Inicio: . F.Lectura: 09/02/2024. ESP. UNIVERSIDAD DE NAVARRA. .
Tailoring the bioactivities of IL-12 for Cancer immunocytokines to armored T cell transfer Autores: Di Trani Claudia Augusta | Participantes: Berraondo, Pedro, Melero, Ignacio Javier Tesis Doctoral. F.Inicio: . F.Lectura: 04/07/2023. ESP. UNIVERSIDAD DE NAVARRA. .
Epitope identification for subunit vaccine design: application to prophylactic vaccines against sars-cov-2 and therapeutic vaccines against cancer Autores: APARICIO, BELEN | Participantes: Sarobe, Pablo, HERVAS, SANDRA Tesis Doctoral. F.Inicio: . F.Lectura: 03/07/2023. ESP. UNIVERSIDAD DE NAVARRA. .
CAR DENSITY INFLUENCES ANTITUMORAL EFFICACY OF BCMA CAR T CELLS AND CORRELATES WITH CLINICAL OUTCOME Autores: RODRÍGUEZ, PAULA | Participantes: RODRIGUEZ, JUAN ROBERTO, LASARTE, JUAN JOSE Tesis Doctoral. F.Inicio: . F.Lectura: 02/12/2022. ESP. UNIVERSIDAD DE NAVARRA. .