Bioinformática Traslacional
INFORMACIÓN DE CONTACTO
Grupo de Investigación
Aguilar F, Lozano JJ, Clària J, Reinartz Groba SN, Richter M, Jiménez-Gracia L, Grange P, Jolly A, Praktiknjo M, Sánchez-Garrido C, Uson Raposo EM, García-Torre B, Laleman W, Gómez-Cabrero D, Palomino-Echeverria S, Iglesias EH, Farias AQ, Marciano S, Caraceni P, Trebicka J, Cerutti A, Arroyo V, Heyn H, Nieto JC, Soehnlein O, Rautou PE, Moreau R
"Maladaptive emergency granulopoiesis predicts poor outcomes in patients hospitalized with decompensated cirrhosis.".
J. Hepatol.. 84(4): 749 - 765. 2026. [doi:10.1016/j.jhep.2025.11.012]
Cenzano, I, Cócera, M, Lopez-Perez, AR, Campos-Dopazo, L, Ruiz, J, Sancho, I, Martin-Uriz, PS, Aguirre-Ruiz, P, Sarvide, S, Vilas-Zornoza, A, Ripalda-Cemborain, P, Alignani, D, Lopez, A, Barrios, MM, Agreda, DQ, Ye, J, Lehmann, R, Sudupe, L, Abengozar-Muela, M, Lopez-Janeiro, A, Tamariz-Amador, L, Muiños-López, E, Saez, B, Tegner, J, Calvo, IA, Gomez-Cabrero, D, Prosper, F
"Single-Cell Profiling Reveals RAB13+Endothelial Cells and Profibrotic Mesenchymal Cells in Aged Human Bone Marrow".
Aging Cell. 25(4): e70475. 2026. [doi:10.1111/acel.70475]
García, B, Conty, A, Fernández-Celis, A, Mouzo, D, Gil, C, Garmendia-Antoñana, N, Navascues, A, Ezpeleta, C, Solano, C, Pasquier, I, Alvarez, V, Sádaba, R, Gómez, D, López-Andres, N, Lasa, I
"Dual transcriptomic profiling of Staphylococcus aureus endocarditis in a porcine model reveals strong parallels with human infection".
mBio. 16(12). 2025. [doi:10.1128/mbio.02316-25]
Muiños-Lopez, E, Lopez-Perez, AR, Sudupe, L, Vilas-Zornoza, A, Sarvide, S, Ripalda-Cemborain, P, Aguirre-Ruiz, P, Martin-Uriz, PS, Larrayoz, M, Alvarez-Gigli, L, Abengozar-Muela, M, Cenzano, I, Cocera, M, Ruiz, J, Sancho, I, Bantan, A, Kurowska, A, Ye, J, Newton, PT, Paiva, B, Tamariz-Amador, LE, Rodriguez-Madoz, JR, Lagani, V, Tegner, J, Saez, B, Martinez-Climent, JA, Calvo, IA, Gomez-Cabrero, D, Prosper, F
"Characterization of the bone marrow architecture of multiple myeloma using spatial transcriptomics".
Commun. Biol.. 8(1): 1620 - 1620. 2025. [doi:10.1038/s42003-025-08975-z]
Mouzo, D, Ortega-Legarreta, A, Lopez-Perez, AR, Planell, PN, San Martin-Uriz, P, Vilas-Zornoza, A, Aguirre-Ruiz, P, Jauregui, LP, Martinez-Turrillas, R, Rifón, J, Lagani, V, Lehman, R, Tegner, J, Perez-Rodriguez, M, Navarro, S, Bueren, JA, Rio, P, Rodriguez-Madoz, JR, Gomez-Cabrero, D, Prosper, F
"Single-cell multiomic dissection of human hematopoietic stem cells reveals novel transcriptional fingerprints and regulatory programs in bone marrow and mobilized peripheral blood".
Blood. 146: 1377 - 1378. 2025. [doi:10.1182/blood-2025-1377]
Planell, N, Martínez-de-Morentin, X, Mouzo, D, Lara-Astiaso, D, Vilas-Zornoza, A, Martín-Uriz, PS, Alignani, D, Paiva, B, Maillo, A, Kurowska, A, Berastegui, N, Garcia-Olloqui, P, Urdangarin, A, Noori, P, Ortega-Legarreta, A, Hernaez, M, Lagani, V, Kiani, N, Merkenschlager, M, Ezponda, T, Martín-Subero, JI, Ramírez, RN, Tegner, J, Prosper, F, Gomez-Cabrero, D
"Uncovering the regulatory landscape of early human B cell lymphopoiesis and its implications in the pathogenesis of B-ALL".
Sci. Adv.. 11(41): eadw3110. 2025. [doi:10.1126/sciadv.adw3110]
Ortega-Legarreta, A, Maillo, A, Mouzo, D, López-Pérez, AR, Kular, L, Kakhki, MP, Jagodic, M, Tegner, J, Lagani, V, Ewing, E, Gomez-Cabrero, D
"GeneSetCluster 2.0: a comprehensive toolset for summarizing and integrating gene-sets analysis".
BMC Bioinformatics. 26(1): 219 - 219. 2025. [doi:10.1186/s12859-025-06249-3]
Flores-Costa, R, Duran-Güell, M, Romero-Grimaldo, B, Contreras, BJ, Salvatella, A, Sánchez-Rodríguez, MB, Uschner, F, Klein, S, Diaz, A, Huergo, E, Gómez-Cabrero, D, Bosch, J, Rautou, PE, Trebicka, J, López-Vicario, C, Clária, J
"An optimized peritonitis-induced ACLF model that reproduces the full spectrum of extrahepatic organ failures in mice".
Hepatol. Commun.. 9(7): e0744. 2025. [doi:10.1097/HC9.0000000000000744]
Huergo, E, López-Pérez, AR, Vallerga, CL, López-Vicario, C, Palomino-Echeverria, S, Planell, N, Lagani, V, Aguilar, F, Sierra, P, Caraceni, P, Farias, AQ, Trebicka, J, Clária, J, Rautou, PE, Meurs, JBJV, Gomez-Cabrero, D
"Patients with acute decompensation of cirrhosis present a unique methylation signature associated with their outcome".
J. Hepatol.. 82. 2025.
Wirtz, TH, Palomino, S, Pollmanns, MR, Huergo, E, Schreibing, F, Reissing, J, Sanchez, C, López-Vicario, C, Aransay, AM, Baldassarre, M, Zaccherini, G, Pompili, E, Schulz, M, Uschner, FE, Klein, S, Gu, WY, Schierwagen, R, Valainathan, S, Verbeeck, A, Campion, D, Giovo, I, Koch, A, Kramann, R, Bruns, T, Kiani, N, Caraceni, P, Alessandria, C, Moreau, R, Trebicka, J, Claria, J, Planell, N, Rautou, PE, Trautwein, C, Gómez-Cabrero, D
"Single-cell RNA sequencing of peripheral blood mononuclear cells in patients with acutely decompensated cirrhosis reveals a specific monocyte subset associated with an increased risk of progression to ACLF".
J. Hepatol.. 82. 2025.
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